Enabling Technologies in Pharmaceutical and Chemical Development

“Unlock the power of technology to drive creative chemical synthesis and impactful innovation”

  • Next Date

    April 14, 2025

  • Length

    4 days

  • Format

    In-person

  • Investment

    2700€ *

Enabling Technologies in Pharmaceutical and Chemical Development
Overview

The “Enabling Technologies in Pharmaceutical and Chemical Development” course is an innovative and international program designed to introduce cutting-edge technologies for pharmaceutical and chemical development. It strengthens laboratory techniques, encouraging creative chemical synthesis and promoting impactful innovation in sustainable practices.

Participants will gain comprehensive knowledge in the latest tools and techniques transforming the landscape of chemistry. The course covers a variety of technologies, including flow chemistry, electrochemistry (with hands-on sessions), photocatalysis, biocatalysis, machine learning, artificial intelligence, and membrane technology. Additionally, high-throughput synthesis, chemical development, and scale-up in the pharmaceutical and chemical industries will be explored, empowering chemists with the skills needed to excel.

As scientific progress advances, the need to harness new technologies and integrate diverse disciplines becomes critical. This course emphasizes continuous processing and control as key design elements in synthetic procedures.

 

*Investment

Participants can: assist the entire course; or assist some modules (per day)

 

Industry| Base course: 2700€ (all week)- 750€ (per day)

 

Academics and Researchers : Base course- 700€

 

Students: Base course- 400€

Course Content

The “Enabling Technologies in Pharmaceutical and Chemical Development” course offers a unique opportunity to learn from industrial experts in various fields. Participants will explore key themes fundamental to success in chemical synthesis through modules led by internationally recognized scientists.

 

Program Structure

 

Day 1:

  • Fundamentals and concepts of flow chemistry.
  • Integration of flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry.

 

Day 2:

  • Fundamentals and concepts of electrosynthesis
  • Hands-on Electrosynthesis Module
  • Laboratory session on electrosynthesis technology to improve chemical reactions and processes.

 

Day 3:

  • Enabling Chemical Technologies and Scale-up
  •  High-throughput and scale-up of chemical processes.
  • Case Studies and Applications
  • Real-world examples and protocols for applying enabling technologies in API synthesis.

 

Day 4:

  • Fundamentals and concepts of machine learning and artificial intelligence
  • Chemical Engineering Technologies
  • Use of membrane-based technologies to improve sustainability in chemical reactions and processes.

 

Expert Instructors

 

Flow Chemistry in Industry: Dr. Jesus Alcazar (Johnson & Johnson Innovative Medicine)

Electrochemistry in Industry: Dr. Robert Green (Vertex Pharmaceuticals), Prof. Dr. Kevin Lam (University of Greenwich)

Machine Learning & AI: Dr. César A. Urbina-Blanco, Dr. Daniela Blanco (Sunthetics)

Biocatalysis: Dr. Erika Tassano (Novartis Biomedical Research)

High-throughput and New Technologies: Dr. Darren Poole (GlaxoSmithKline)

Scale-up Chemistry: Dr. Antal Harsányi (Jiuzhou Pharma)

Membrane Technology: Andrew Baum (Evonik)

Learning Outcomes

The course aims to prepare researchers to address challenges and opportunities arising from incorporating new technologies into chemical synthesis. Participants will learn to adapt traditional protocols and methodologies to technology-driven research and automation.

 

Key objectives include:

 

  • Providing a concise, current overview of enabling technologies.
  • Covering the background, fundamentals, technical aspects, and applications of these technologies in synthesis.
  • Encouraging the implementation of new technologies in chemical processes.
  • Diversifying research in chemical synthesis by highlighting the benefits of machine assistance.
  • Analyzing chemical processes to propose alternative and sustainable routes using new technologies.
  • Handling equipment and solving problems associated with chemical synthesis.

Participants Profile

This course is tailored for pre-and post-doctoral scientists (Master and PhD level) from industry and academia interested in advancing their knowledge in enabling technologies for chemical synthesis. It builds on participants’ existing knowledge of organic chemistry and chemical engineering, emphasizing applications in the synthesis and catalysis of APIs.

 

Who should apply:

  • Chemists (PhD or Master level) working in industry
  • Chemistry students and employees of chemical industry and R&D institutions
  • Educators and academics looking to enhance their understanding of enabling technologies

 

Program Coordination
Maria Manuel Marques

Associate Professor with Habilitation at NOVA FCT

Maria Manuel Marques is Associate Professor with habilitation from the chemistry department at NOVA School of Science and Technology – Universidade NOVA de Lisboa(NOVA FCT) and
member of LAQV-Requimte. She is the head of the Organic Synthesis and Chemical Biology group at NOVA FCT.
Maria Manuel Marques is passionate for innovative and sustainable synthetic methodologies. Her research revolves around the exciting interface of chemistry and biology. Through her extensive research, she explores innovative ways to address complex synthetic challenges, particularly the synthesis of medicinally relevant heterocyclic scaffolds, and glycopeptides in order to understand biological systems. She studied in Portugal and Austria and has been a visiting researcher at Universities in Europe. She has been the coordinator of national and international projects in competitive funding calls, and is highly committed to mentoring and supervision.

Faculty Portal

Kevin Lam

Professor of Synthetic Electrochemistry at the University of Greenwich

In 2010, Kevin Lam received his PhD in Medicinal and Synthetic Organic Chemistry from the Catholic University of Louvain in Belgium, under the supervision of Professor Istvan Marko. His doctoral work explored the use of electrochemistry and photochemistry as green alternatives to activate organic molecules. This work resulted in the development of a new radical-based deoxygenation reaction (the Lam-Marko reaction).

After his PhD, he moved to the University of Vermont (UVM). His research focused on applying analytical/physical electrochemistry alongside spectroscopy to study the complex redox behaviour of organometallic compounds.

This work bolstered the use of weakly coordinating electrolytes/solvents as an electrochemical medium to allow for the generation and characterisation of highly reactive and unstable 17e- organometallic radical-cations. Additional work at UVM led to the pioneering of a new method to modify electrode surfaces through an ethynyl linkage. The covalent attachment of molecules to an electrode surface is fundamental to the field of molecular electronics and numerous material applications.

In 2013, accepted a position of Assistant Professor at Nazarbayev University in Astana. During his time in Kazakhstan, Kevin developed a new research program in the field of Molecular Electrochemistry. His work led to the development of new organometallic anticancer compounds as well as to the discovery of novel, efficient and green electrocatalysts for CO2 recycling.

In 2023, Kevin was promoted to Professor of Synthetic Electrochemistry at the University of Greenwich in the UK, where he continues his interdisciplinary research.

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