The Enabling Technologies for Chemical Synthesis course offers a unique opportunity to learn from experts in the fields of flow chemistry, electrochemistry, mechanochemistry, photo- an biocatalysis, membrane technology, supercritical fluids, ultra-high pressure and machine learning and artificial intelligence. This course unlocks the potential of technology to improve the development of chemical processes by training professionals in the chemical and pharmaceutical fields.

Throughout the course modules, participants will explore key themes fundamental to success in the chemical synthesis, lectured by internationally recognized scientists in the field.

The Program is organized into three modules:

• The Sustainable Chemical Technologies module addresses fundamentals and concepts of flow chemistry, electrochemistry, mechanochemistry, machine learning and artificial intelligence. This module offers information on novel methodologies, providing an easy-to-understand, concise, and current overview of the different technologies, parameters to be considered and the set-up of experiments. The integration of flow chemistry, high-throughput experimentation, scale-up(out), and photoelectrochemistry will be covered. Examples will be given, and protocols will also be addressed and analysed to provide a deeper understanding of how those technologies can be used in the synthesis of APIs.

Flow Chemistry

Prof. Dr. Stefan Bräse (Karlsruhe Institute of Technology – KIT)

Electrochemistry

Prof. Dr. Kevin Lam (The University of Greenwich)

Mechanochemistry

Prof. Dr. Evelina Colacino (Université de Montpellier)

Machine Learning & AI

Dr. Teodoro Laino (IBM Research Europe – Zurich)

• The Enabling Catalytic Technologies module aims to provide participants with an easy-to-understand, concise, and current overview of the fundamentals of photocatalysis and biocatalysis. This module will encourage participants to implement photocatalysis and biocatalysis in chemical synthesis laboratories.

Photocatalysis

Prof. Dr. Burkhard König (Regensburg University)

Biocatalysis

Prof. Dr. Jan Deska (University of Helsinki)

• In the Chemical Engineering Technologies module, the participants will acquire knowledge on the use of supercritical fluids, ultra-high pressure and membrane-based technologies to improve the sustainability of chemical reactions and chemical processes.

Membrane Technology

Prof. Dr. Andrew Livingston (Queen Mary University of London)

Supercritical fluids

Prof. Dr. Walter Leitner (Max Planck Institute for Chemical Energy Conversion)

Ultra-high Pressure

Prof. Dr. Isabelle Chataigner (Université de Rouen Normandie)

The course will also include a Hands-on module, which consists of laboratory sessions where participants will be able to experiment with how the varied technologies can be used to improve chemical reactions and processes. At the end of this course, the participant will have acquired knowledge, skills and competencies related to the concept of enabling technologies for chemical synthesis, the application of new technologies and the integration of different technologies for the chemical and pharmaceutical industry.

In summary, the course Enabling Technologies for Chemical Synthesis offers a unique combination of contents both theoretical and practical content, with face-to-face classes with internationally recognized experts covering key technologies for the sustainability and success of the chemical and pharmaceutical industry, providing benefits in academic and industrial environments.

The learning objectives of the course on Enabling Technologies for Chemical Synthesis aim to prepare researchers capable of addressing upcoming challenges and opportunities arising from the incorporation of new technologies in chemical synthesis. The aim is to train participants who work in chemical synthesis and related fields to use and adapt the traditional protocols and methodologies to technological-driven research and automation. The participants will acquire the knowledge, skills and competencies necessary to address the current challenges in chemical synthesis and to drive impactful innovation with the application of new technologies and the integration of different technologies for the chemical and pharmaceutical industry.

The learning outcomes of the course Enabling Technologies for Chemical Synthesis are:

• Provide an easy-to-understand, concise, and current overview of Enabling Technologies.
• Provide the background, fundamentals, technical aspects, methods, and a deep discussion on the application of these technologies in synthesis.
• Unlock the potential and encourage the implantation of new technologies in chemical processes.
• Improve and diversify research in chemical synthesis by highlighting the benefits of the use of machine assistance with a broader view across all synthesis environments.
• Analyse a chemical process and propose alternative and sustainable routes applying new technologies.
• Manipulate the equipment and solve problems associated with chemical synthesis.